Wednesday, September 15, 2010

The tell-tale signs of arthritis

Thousands of people with the tell-tale signs of arthritis are taking up to 10 years off their lives by putting off going to see their doctor, experts have warned.

A study has shown there is a crucial 'three-month window' when rheumatoid arthritis - which causes stiff, swollen and sore joints - can be slowed down and even stopped in its tracks.

The research suggests the toll of the disease in Britain could be scaled back if it is caught within these early months when symptoms first appear in patients.

But most sufferers with painful knuckles and toes wait longer before visiting their GP.

Left untreated or tackled too late, the crippling condition can lead to people giving up work. Poorly treated rheumatoid arthritis also raises the risk of heart attacks and other cardiac problems.

Dr Karim Raza, a consultant rheumatologist, said: 'Recent trial data has shown that there is a three-month window after the start of symptoms and if you look at the molecules in the joints at that time they are different from what they are at a later stage.

'The data suggests that if you intervene within those three months you can very rapidly slow progression of the disease and in some cases halt it.

'There is also a suggestion that if you intervene aggressively you might in a small proportion of people actually switch off the disease.'

He added: 'A quarter of patients stop working within the first five years of diagnosis.

'And the condition doesn't just affect the joints. On average, people with rheumatoid arthritis die 10 years younger than people without rheumatoid arthritis.'

Modern medicine allows the condition, in which the immune system attacks the joint, to be quickly diagnosed and, in many cases to be effectively treated.

Studies show that given early enough, methotrexate and other pills available on the NHS, can greatly slow the progress of the condition and, in some cases even halt it all together.

But they are most effective if given within the first three months of someone developing early symptoms such as swollen and painful joints.

In extreme cases, eight years pass between the first signs of rheumatoid arthritis and the prescription of pills, the British Science Festival heard.

Dr Raza, whose research is partly funded by Arthritis Research UK, said: 'The patient is the main culprit. On average, patients spent three months thinking about whether to see their GP.

'People think that developing aches and pains is part and parcel of life. They don't think it is serious or they don't want to waste their GPs time.'

One of the most common of the 200 or so types of arthritis, the condition affects twice as many women as men.

Tell-tale signs include a stiffness of the fingers and toes that wears off over the course of the day, rather than worsening with exercise.

The knuckles and other finger joints are particularly susceptible, as the joints between the toes and foot, with both sides of the body affected equally.

Although the rheumatoid arthritis is most common after the age of 40, it can occur at any age.

In osteoarthritis, the most common form of the condition, the problems are not caused by the immune system but by the cartilage that takes the strain in joints getting worn way.

Dr Raza added that the development of tests that would allow the better matching of drugs to patients could see some patients cured by early treatment.

'That's the Holy Grail,' he said. 'There is a precedent in the cancer literature - the more you understand what's going on in a tumour, the more you're able to target treatments and the better the outcomes. We'd like the same to be true of rheumatoid arthritis.'

A spokesman for Arthritis Research UK said: 'The average delay of 12 weeks between the onset of symptoms and going to the GP is something that needs to be urgently tackled, as we know that early diagnosis and treatment of rheumatoid arthritis is vital if we want to get the condition under control quickly to prevent joint damage.

'Many people are not aware of rheumatoid arthritis nor how serious it can be, and assume aches and pains in their joints are something to do with over-doing exercise or gardening.

'We have a lot of work to do in raising awareness of rheumatoid arthritis among the general public so that they know to seek their GP's advice as soon as they develop symptoms.'

Monday, August 30, 2010

The study included 123 people allergic to ragweed

"People with hay fever react differently when ragweed allergy season arrives. Some start sneezing right away, and others don't, so we wanted to determine what makes certain people develop symptoms more quickly," said allergist Anne K. Ellis, MD, lead author of the study and an ACAAI member. "We tested a number of common perennial allergens and found that having an allergy to cats, dogs or dust mites sets hay fever sufferers up for faster onset of symptoms when exposed to ragweed."

The study included 123 people allergic to ragweed. Of those, 66 percent tested positive for cat allergies, 63 percent tested positive for dog allergies and 73 percent tested positive for dust mite allergies. All were exposed to ragweed for three hours in a special controlled room called the Environmental Exposure Unit (at Kingston General Hospital, Ontario), and completed symptom questionnaires every 30 minutes during exposure.

"On average, those who tested positive for cat, dog or dust mite allergies developed symptoms either faster than, or to a greater degree than those who tested negative for those allergies," said Dr. Ellis. "The differences seen at 90 minutes of exposure were less dramatic after 3 hours of exposure, however. That suggests that once the hay fever season is in full swing, the symptom differences between those with cat, dog or dust mite allergies and those without no longer exist."

Sunday, August 22, 2010

Vitamin D - effective therapeutic agent to treat or prevent allergy to a common mold

Research conducted by Dr. Jay Kolls, Professor and Chair of Genetics at LSU Health Sciences Center New Orleans, and colleagues, has found that vitamin D may be an effective therapeutic agent to treat or prevent allergy to a common mold that can complicate asthma  and frequently affects patients with Cystic Fibrosis. The work was scheduled to be published online August 16, 2010, ahead of the print edition of the September 2010 issue of the Journal of Clinical Investigation.

The environmental mold, Aspergillus fumigatus, is one of the most prevalent fungal organisms inhaled by people. In the vast majority, it is not associated with disease. However, in asthmatics and in patients with Cystic Fibrosis (CF), it can cause significant allergic symptoms. Up to 15% of CF patients develop a severe allergic response called Allergic Bronchopulmonary Aspergillosis (ABPA). Since the mold is so common, the researchers wanted to identify the factors that determine why only a subset of patients develop the allergy and what factors regulate tolerance or sensitization to the mold resulting in the development of ABPA. To gain insights, the group studied two groups of patients with CF. Both groups were colonized with A. Fumigatus, but only one had ABPA.

The researchers focused on Th2 cells - the hormonal messengers of T-helper cells that produce an allergic response. They found that a protein called OX40L was critical in driving Th2 responses to A. fumigatus in the CD4+T cells isolated from patients with ABPA and that this group had a much greater Th2 responses to A. Fumigatus. The CD4+T cells from the group of patients that did not have ABPA had higher levels of the proteins, FoxP3 and TGF-ß, critical to the development of allergen tolerance. The researchers discovered that heightened Th2 reactivity in the ABPA group correlated with a lower average blood level of vitamin D.

"We found that adding vitamin D not only substantially reduced the production of the protein driving an allergic response , but it also increased production of the proteins that promote tolerance," notes Dr. Jay Kolls, Professor and Chair of Genetics at LSU Health Sciences Center New Orleans.

According to the National Institutes of Health, Cystic fibrosis (CF) is the most common, fatal genetic disease in the United States. About 30,000 people in the United States have the disease. CF causes the body to produce thick, sticky mucus that clogs the lungs, leads to infection, and blocks the pancreas, which stops digestive enzymes from reaching the intestine where they are required in order to digest food. It is estimated that about 70,000 people worldwide have the disease.

Recent research has suggested that low levels of vitamin D may contribute to heart disease, a higher risk of diabetes, certain cancers, and depression as well as asthma, colds, and other respiratory disorders.

"Our study provides further evidence that vitamin D appears to be broadly associated with human health," notes Dr. Jay Kolls, Professor and Chair of Genetics at LSU Health Sciences Center New Orleans. "The next step in our research is to conduct a clinical trial to see if vitamin D can be used to treat or prevent this complication of asthma and Cystic Fibrosis."

Friday, June 11, 2010

There are three types of body fat

Skinfold self-testing at home
There are three types of body fat: The first is subcutaneous fat, which is stored
right below your skin. Second, there's intramuscular fat, which is inside the muscle
tissue (picture the fat inside a "marbled steak."). Third, you have internal fat,
which is located on and around your internal organs for protective cushioning.
Skinfold testing is based on the premise that the majority of your body fat is
subcutaneous– right below your skin where you can see and grab it. By "pinching"
the skin and fat and measuring the thickness of the fold at one or more sites, you
can get a fairly accurate estimate of your total body fat percentage...and more
importantly, a way to consistently measure your progress from week to week.
Until quite recently, a challenge many people faced was not having an experienced
fitness professional available to test you. For years, a skinfold test could only be
performed by somebody else (there was no way to "pinch yourself.") A second
person was required to "pinch your fat" at several locations, including spots you
can't reach, such as your upper back. Even if you were the "human pretzel" and
you could somehow reach around and measure all your own skinfolds, it wouldn't
be accurate.
This problem was surmounted when a company called Accu-Fitness invented an
inexpensive plastic skinfold caliper called the Accu Measure. The Accu Measure is
different from other calipers because it was designed so you can measure your
own body fat at home and you don't even need another person to help! This
method is inexpensive, convenient and private!
There's a LOT to be said for the accountability factor when you have a coach or
trainer measure your body fat every week. However, the privacy factor of the Accu
Measure is also nice because if you're like most people, you prefer not to have a
stranger groping your fat rolls every week. It's kind of embarrassing in the
beginning... although once you start getting leaner, you may surprise yourself
when one day you're proud to have someone "pinch you" - because there's nothing
there but thin skin on top of rock hard muscle!)

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Wednesday, June 9, 2010

Is β-Carotene and Other Carotenoids Important in Cancer Prevention?

Is β-Carotene and Other Carotenoids Important in
Cancer Prevention?
β-Carotene and other carotenoids has long been speculated as reducing
the risk of cancer. In accordance, several studies of populations have
suggested that when people ate more carotenoids the presence of cancer
was lower. Interestingly, while β-carotene often receives the most atten-
tion other carotenoids have been shown to strong benefit as well. For
example, studies involving smokers have suggested that the dietary intake
of total carotenoids, lycopene, β-cryptoxanthin, lutein, and zeaxanthin
have a more clear relationship to reducing lung cancer risk. Thus it makes
sense to eat a diet rich in fruits and vegetables to allow for a broad variety
of carotenoids and to plan a supplementation regimen along this line of
thinking as well.
Arimidex is approved for postmenopausal women with hormone receptor-positive early breast cancer.

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Sunday, June 6, 2010

The environment that we inhabit

    The Very Basics of Humans
   All that we (our body) are, ever were, or are going to be is borrowed
from the environment that we inhabit. This unique state of indebtedness
is primarily attributed to our nutrition intake. We must be grateful to the
earth's crust for lending us minerals that strengthen our bones and teeth
and allow us to have electrical operations that drives nerve and muscle
function. We must also pay homage to plants for the carbohydrate forms
that power our operations and for the amino acids that make the protein
in our muscle.
    Nutrition refers to the science of nourishing our body.
   All too often we do not truly appreciate the relevance of nutrition to
our basic being. But again, please keep in mind that nearly everything we
are and are able to do is either a direct or indirect reflection of our past
and current nutrition intake. No matter how oversimplified nutrition
may seem in television commercials and on cereal boxes, it is without a
doubt one of the most complex and interesting sciences out there. One of
the major tasks of this site is to provide an understandable overview of
nutrition as it applies to optimal health and longevity.

Wednesday, May 26, 2010

I was aware of the natural methods of treatment

I underwent a barium meal examination which indicated "
Chronic doudenitis, may be chronic duodenal ulcer." The numerous drugs prescribed for the
treatment of this ailment and the continuing weakness and heaviness of my left side made my
condition worse still. I endured this for three years, until the pain and heaviness of the left side
was miraculously cured by an astrologer : But nothing could rid me of the heartburn, abdominal
pain and occasional severe stomach upsets, which continued to necessiate the use of several
drugs. Investigations, from time to time, confirmed the diagnosis of duodenitis or chronic
duodenal ulcer. A barium meal examination , done when I was 39, revealed hiatus hernia with
peptic oesophegal ulcers.
To add to all of this, at 45, an eminent heart specialist declared me a heart patient, following a
check-up due to pain on the left side of my chest. The heavy drugging, dieting etc. that ensued completely ruined my health and resulted in insomnia and a weight loss of 15 kg. Consulting
another eminent heart specialist two years later, I was informed that there was no evidence
whatsoever of heart trouble, but he confirmed the presence of hiatus hernia and stomach
trouble. God alone knows which diagnosis was correct : Then came a host of diseases in rapid
succession - spondylosis, myalgia, backache and prostate enlargement, in treating all of which
the modern medical system failed to give me any relief, despite taking huge quantities of drugs,
especially painkillers, antacid tablets and tranquillisers.
All this time, I was aware of the natural methods of treatment ...

Wednesday, May 19, 2010

The calorie theory is as follow

The calorie theory is as follows :


If a particular individual needs 2,500 calories a day and consumes only 2,000, a 500 calorie deficit results. To compensate for the deficit, the body will draw on its fat reserves to find an equivalent amount of energy, and weight loss will result. If, on the other hand, an individual has a daily intake of 3,500 calories when only 2,500 are needed, the excess 1,000 calories will automatically be stored as body fat.


The theory is therefore based on the assumption that there is no loss of energy. It is purely mathematical, drawn directly from Lavoisier's theory on the laws of thermodynamics.


At this point we may well be wondering how it was that prisoners in Nazi concentration camps managed to survive for almost five years on only 700 to 800 calories a day. If the calorie theory was correct, the prisoners should have died once their body fat was used up in other words, within a few months.


Similarly, we may wonder how people with big appetites who consume 4,000 to 5,000 calories a day are not fatter than they are (some even remain skinny). If the calorie theory was correct, these hearty eaters would come to weigh 60 to 80 stone within a few years.


Furthermore, how can you explain why some people continue to put on weight even when they reduce their daily calorie intake by eating less? Thousands of people go on gaining weight like this while starving themselves to death.

Tuesday, May 18, 2010

mitochondrial dysfunctions

Aging is associated with mitochondrial dysfunctions, which trigger membrane leakage, release of reactive species from oxygen and nitrogen and subsequent induction of peroxidative reactions that result in biomolecules' damaging and releasing of metals with amplification of free radicals discharge. Free radicals induce neuronal cell death increasing tissue loss, which could be associated with memory detriment. These pathological events are involved in cardiovascular, neurodegenerative and carcinogenic processes. Dietary bioactive compounds from different functional foods, herbs and nutraceuticals (ginseng, ginkgo, nuts, grains, tomato, soy phytoestrogens, curcumin, melatonin, polyphenols, antioxidant vitamins, carnitine, carnosine, ubiquinone, etc.) can ameliorate or even prevent diseases. Protection from chronic diseases of aging involves antioxidant activities, mitochondrial stabilizing functions, metal chelating activities, inhibition of apoptosis of vital cells, and induction of cancer cell apoptosis. Functional foods and nutraceuticals constitute a great promise to improve health and prevent aging-related chronic diseases.

Tuesday, May 11, 2010

Chamomile extract in preventing inflammation and cancer

Inducible cyclooxygenase (COX-2) has been implicated in the process of inflammation and carcinogenesis. Chamomile has long been used in traditional medicine for the treatment of inflammatory diseases. In this study we aimed to investigate whether chamomile interferes with the COX-2 pathway. MAIN METHODS: We used lipopolysaccharide (LPS)-activated RAW 264.7 macrophages as an in vitro model for our studies. KEY FINDINGS: Chamomile treatment inhibited the release of LPS-induced prostaglandin E(2) in RAW 264.7 macrophages. This effect was found to be due to inhibition of COX-2 enzyme activity by chamomile. In addition, chamomile caused reduction in LPS-induced COX-2 mRNA and protein expression, without affecting COX-1 expression. The non-steroidal anti-inflammatory drug, sulindac and a specific COX-2 inhibitor, NS398, were shown to act similarly in LPS-activated RAW 264.7 cells. Our data suggest that chamomile works by a mechanism of action similar to that attributed to non-steroidal anti-inflammatory drugs. SIGNIFICANCE: These findings add a novel aspect to the biological profile of chamomile which might be important for understanding the usefulness of aqueous chamomile extract in the form of tea in preventing inflammation and cancer .

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Tuesday, April 13, 2010

Allowing Plan B drug maker

The FDA has complied with a federal court order issued on March 23, 2009, by allowing Plan B drug maker, Barr Pharmaceuticals Inc, now part of Teva Pharmaceutical Industries Limited, to submit an application for approval for the pill to be made available to women 17 and older without a prescription. The court order directed the FDA to comply with within 30 days of the decision. Based on scientific findings made in 2005 by the Center for Drug Evaluation and Research, the agency has decided not to file an appeal. In as little as ten months, seventeen-year-old girls will have access to the emergency contraception, commonly called the "morning after" pill, without a prescription. Prior to the March court order, the nonprescription use of Plan B had been restricted to those eighteen and older, although Barr Pharmaceuticals had previously sought access for girls sixteen years of age and older.Many conservative groups oppose nonprescription access to Plan B, arguing that it's easy access could lead to promiscuity and could possibly become a tool for sexual predators and criminals running prostitution rings. However, women's health advocates are exuberant over decision with their belief that because Plan B is safe and effective in preventing unwanted pregnancy, it could help reduce the number of abortions. In addition, many believe that Plan B should be made available with no age restrictions arguing that it is crucial for women to have fast access to the drug, as it is highly successful in preventing pregnancy when used within twenty-four hours of having sexual intercourse. In a statement, Wendy Wright, president of the conservative group Concerned Women for America said, "The FDA violated its standards when it made the high dose Plan B available nonprescription to adults. But now the FDA is making the drug available to minors without parental consent." She then added, "The FDA should have challenged the decision." Others who oppose the relaxed access to the contraceptive say that Plan B is the equivalent of an abortion pill as it can prevent a fertilized egg from attaching to the uterus. Recent research suggests that this is a possibility, although an unlikely one. According to Nancy Northup, president of the Center for Reproductive Rights, which initiated the lawsuit in 2005, "It's a good indication that the agency will move expeditiously to ensure its policy on Plan B is based solely on science." Amy Allina, policy director of the National Women's Health Network, stated that the FDA's decision "gets us part way to where we believe the FDA should be." However, she also noted, "Putting it behind the counter does not make it safer or more effective. In fact, because it creates another barrier it's likely to make it less effective." The Plan B dosage consist of two pills that contain higher amounts of progestin than are used in prescription birth control pills. It works by preventing ovulation or fertilization and when taken within 72 hours of having unprotected sex, it can reduce the chances of pregnancy by as much as 89 percent. The treatment sells for $35 to $60 and women must ask for Plan B at the pharmacy counter and provide identification having proof of age. According to Teva, even with restrictions, sales of Plan B "have more than doubled" since becoming available to adults from pharmacists in 2006.



Wednesday, March 31, 2010

Evening primrose seeds contain an oil with a high concentration

Evening Primrose Oil for Lowering Cholesterol

Evening primrose seeds contain an oil with a high concentration of compounds rarely found in plants: essential fatty acids, specifically gamma-linolenic acid. In one study, reported in The Review of Natural Products, 79 people with high cholesterol took 4 grams of Efamol every day for three months (which provides about 320 mg of GLA), and their average cholesterol level fell 31.5 percent. The suggested dose for evening primrose oil starts at 1-gram gelcaps twice or three times a day. High cholesterol requires professional care, so consult your physician about GLA.


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Tuesday, March 30, 2010

VITAMIN B3 (Niacin) Essential for proper circulation and healthy skin

VITAMIN B3 (Niacin) Essential for proper circulation and healthy skin. Increases energy, aids digestion, helps prevent migranes. HERBAL SOURCES: Alfalfa, burdock root, catnip, cayenne, chamomile, chickweed, eyebright, fennel seed, hops, licorice, mullein, nettle, oat straw, parsley, peppermint, raspberry leaf, red clover, rose hips, slippery elm, yellow dock.


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Saturday, March 27, 2010

Scientific theories Echinacea

Echinacea
Uses based on tradition or theory 
The below uses are based on tradition or scientific theories. They often have not been thoroughly tested in humans, and safety and effectiveness have not always been proven. Some of these conditions are potentially serious, and should be evaluated by a qualified healthcare provider.
Abscesses, acne, attention deficit hyperactivity disorder (ADHD), bacterial infections, bee stings, boils, burn wounds, diphtheria, dizziness, eczema, gingivitis, gum inflammation (pyorrhea), hemorrhoids, herpes labialis, HIV/AIDS, influenza, malaria, menopause, migraine headache, mouth sores, nasal congestion/runny nose, pain, psoriasis, rheumatism, skin ulcers, snake bites, stomach upset, syphilis, tonsillitis, typhoid, urinary disorders, urinary tract infections, whooping cough (pertussis).

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Saturday, March 20, 2010

Obama quit smoking for good.

Doctors say President Obama is "fit for duty," but that doesn't mean he's making all the right lifestyle choices.


After the president underwent a 90-minute physical exam at the National Naval Medical Center Sunday morning, Navy Capt. Jeffery Kuhlman, the chief White House physician, declared him to be in "excellent health."

But Kuhlman still had some healthy recommendations for the president. First and foremost: "Continue smoking cessation efforts."

Slideshow: America's Unhealthiest Presidents

Dr. Nieca Goldberg, a New York City-based cardiologist, said that despite the president's clean bill of health, he may still be at risk for heart disease, because he is a smoker in a high-stress job.

"It's great that he is physically fit, but it won't counteract the fact that he still smokes," Goldberg said. "To reduce his risk of cardiac disease, you can count his exercising as a benefit, but he needs to quit smoking ."


Goldberg said stress not only can raise a person's blood pressure, but it can cause him to pay less attention to his health.

"Heart disease is bipartisan problem, as we have seen recently with Bill Clinton and Dick Cheney," Goldberg said.

Obama will return for another physical exam next summer when he turns 50. Until then, he is going to have to put some extra effort toward his overall wellness.

"President Obama shows that like all Americans, he is a regular person, he is going to have to work on taking care of his health just like we do," Goldberg said.

Dr. Len Horovitz, attending physician at Lenox Hill Hospital in New York, said he thinks too much emphasis has been put on Obama's fitness.

"Exercise does not reverse effects of smoking on the lung," Horovitz said. "He's thin, which is nice, but smoking is the worst habit out there."

This is not the first time Obama has been advised to kick the habit. In the past, he has used nicotine replacement therapy, most commonly in the form of nicotine gum. African American men are at a much higher risk for stroke and heart disease, conditions that smoking increases the chances of.

"Even a few cigarettes a day triples your risk of heart disease, so it's not like a little bit of smoking is OK," Horowitz said. "Since he is a black man he has higher chance of developing high blood pressure, and even though his blood pressure was very good, the game is not over yet."

Before Obama began his run for president, Michelle Obama told the public that her husband had quit smoking for good.

"The president is great role model in every other health respect besides smoking ," Horowitz said.

Saturday, March 13, 2010

What is Osteo-arthritis?


What is Osteo-arthritis?
Osteo-arthritis (OA) is most common form of arthritis affecting mostly the Knees.

How common is Osteo-arthritis?
Osteo-arthritis is most affecting one out of eight people between the ages of 18 and 79. According to Arthritis Foundation, approximately 16 million Americans suffer from Osteo-arthritis, three times as many women as men. Osteo-arthritis has increased recently due to sedentary lifestyle as people walking less, are more over-weight, eat fast food, junk food etc and are not keeping the muscles toned by doing quality exercises. so they are bound to suffer from knee disorders which is simply gravity and weight leading to wearing-out of cartilages. Also more Osteo-arthritis is seen due to increase in awareness and life expectancy, and increase in treatment modalities.

At what age does osteo-arthritis occur?
Most common age for osteo-arthritis is after 60-65 years and this is a normal course of events like losing hair or getting grey hair. But when it occurs in the late 40's or early 50's, then this is due to bad lifestyle.
How does Osteo-arthritis occurs?
Cartilage contains fluid and elastic tissue, and functions to reduce friction as the joint moves. It acts as a shock absorber and as the sliding surface that covers the ends of bones. Osteo-arthritis results from chemical changes in the cartilage that cause it to break down faster than it can be produced.

Knee starts degenerating with age which is more when there is extra weight, diabetes. gout, autoimmune diseases, etc. Gradually the smooth and shiny cartilage between the two bones of the thigh and leg starts wearing out and the bone strikes bone and this leads to a lot of pain and stiffness, especially early in the morning. There is stiffness in the morning and patient requires to take a few steps before he can walk properly.

Previous infection of the joint may predispose to Osteo-arthritis by altering the chemical makeup of cartilage. The weakened cartilage causes it to wears out due to which bone rubs against bone. ultimately leadings to Osteo-arthritis and increased bone density, which may result in bones that are less able to absorb impacts and to protect cartilage from trauma.
What treatment are available for O.A.?
Till now there was no known cure for Osteo-arthritis. The treatments available were:
Decrease the pain with medicines, Herbs and Heat or cold applications
Supportive measures like Weight loss, Rest, Nutrition / food supplements
Assistive devices to make life easier.
Exercise and Paraffin bath etc
Surgical treatments for severe Osteo-arthritis with significant loss of cartilage. These include :
Arthroscopy for pain relief or to fix the joint
Osteotomy to correct joint deformity
Arthrodesis to immobilize joint by fixing bones
Joint replacement for severe joint deterioration

Surgery for Osteo-arthritis is usually considered a choice surgery unless patient is unfit for surgery. However it may need several months of rehabilitation after surgery and an artificial joint may only last for 10 to 20 years when it may wears out and need repeat surgery.



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Friday, February 26, 2010

Treating both depression can reduce severe pain

Treating both depression and inflammation can reduce severe pain in people with rheumatoid arthritis (RA), Japanese researchers say.

They studied 218 RA patients who provided information about their pain levels, depression symptoms, year of RA onset, smoking and drinking habits and socioeconomic demographics. The researchers collected blood samples from the patients to measure levels of CRP, a protein produced by the liver. Levels of CRP rise during periods of acute inflammation. RA treatments often focus on reducing inflammation.

The study found that inflammation and depression each independently increased the likelihood of severe pain. The combined effects of high CRP levels and depression predicted severe pain even more strongly.

"Results of our research demonstrate the potential for clinicians to improve pain control by addressing their patients' psychological symptoms in addition to conducting anti-inflammatory therapy," study leader Dr. Masayo Kojima said in a news release.

The findings suggest that psychotherapy and/or psychotropic medication might be a priority for RA patients who experience severe pain without elevated levels of CRP.

"A clinical approach that takes into account both the body and the mind could have benefits and could enable optimal pain control," the researchers at Nagoya City University and Nagoya University Graduate Schools of Medicine said in a news release.

The study appears in the August issue of the journal Arthritis Care & Research.

Another report in the same issue found that RA patients with depressed spouses suffered worse disease progression over the one year studied. The Canadian study included 133 married RA patients.

"Our findings highlight the key role played by the spouse in disease course of individuals with RA, and point to the importance of including the spouse in clinical interventions," Anita DeLongis and colleagues at the University of British Columbia said. "The mood and mental health of the marital partner or other key members of the family may be critically important to consider in developing more effective and evidence-based treatment for RA patients."

Arthritis.Antibiotic doxycycline

A common antibiotic may slow the progression of osteoarthritis.

A new study shows that treatment with the antibiotic doxycycline slowed the deterioration of joint tissue in women with osteoarthritis of the knee.

Doxycycline is used to treat a variety of bacterial infections. Previous lab tests with animal and human tissue showed that doxycycline may help preserve joint tissue, say the researchers. They add that this is the first major study of the antibiotic as a potential treatment for osteoarthritis.

Osteoarthritis is a common form of arthritis that causes progressive destruction of the cartilage that cushions the joints. Common symptoms are joint pain and stiffness. When severe, osteoarthritis can cause loss of movement in the affected joint.
Antibiotic for Osteoarthritis?

In the study, which appears in the July issue of Arthritis & Rheumatism, researchers compared the effects of doxycycline to a placebo in about 400 obese women with knee osteoarthritis. Specifically, they measured the impact of treatment on the joint space in the affected knee. More joint space indicates a loss of cartilage and progression of the disease.

The women were randomly divided into two groups and received either 100 milligrams of the antibiotic twice daily or a placebo for up to two and a half years.

After 16 months of treatment, the study showed that the average loss of joint space in the diseased knee was 40% less among those who took doxycycline vs. the placebo. After two and a half years, the average loss among the antibiotic group was 33% less.

Although these results suggest the antibiotic slowed the progression of the osteoarthritis, researchers say it did not reduce the severity of joint pain reported by the participants.

However, researchers say the average level of pain was low in both groups, which may have provided limited opportunity for the treatment to show an effect on pain.

But doxycycline was associated with a reduction in the number of times the patients reported a 20% or more increase in knee pain.

Researchers say the study suggests that the antibiotic may provide benefits in the treatment of osteoarthritis but more studies will be needed to confirm these results.

Antioxidants in pomegranates may thwart osteoarthritis

Researchers aren't making that declaration just yet. But they have found signs that natural compounds called antioxidants in pomegranates may thwart osteoarthritis.

Osteoarthritis is the most common type of arthritis, with more than 20 million patients in the U.S., according to the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS).

The pomegranate study was done at Case Western Reserve University. The researchers included Tariq Haqqi, PhD, a professor of medicine. The results appear in The Journal of Nutrition.
Pomegranate Project

Pomegranate extract was pitted against osteoarthritis in lab tests. That's not the same as tests on people or animals, but it's a first step.

Pomegranate extract did two things in those lab tests. It cut levels of an inflammatory chemical called interleukin-1b (IL-1b). It also curbed enzymes that erode cartilage.

Cartilage is a hard but slippery coating on the end of each bone that helps bones slide smoothly past each other. Osteoarthritis develops when cartilage is broken down; exposed bone breaks down, causing pain, inflammation, and disability.
First Findings

This is the first study to show pomegranate's potential against osteoarthritis, note the researchers.

The results "indicate the pomegranate fruit extract or compounds derived from it may inhibit cartilage degradation in osteoarthritis and may also be a useful nutritive supplement for maintaining joint integrity and function," they write.
Researcher's Comments

"Arthritis is one of the foremost diseases for which patients seek herbal or traditional medicine treatments," says Haqqi in a news release.

"However, all the extracts and herbs have not been scientifically evaluated for their efficacy and safety. Indeed, some of them may even interfere with current treatments," he continues.

"Therefore, careful use of supplements and herbal medicines during early stages of disease or treatment may be made to limit the disease progression," says Haqqi.

As always, discuss any supplement use with your doctor.
Pomegranate Potion

The researchers didn't just crack open a pomegranate and put it in a blender. They also didn't use juice from the supermarket.

Instead, they made their own pomegranate extract from powdered pomegranate. Sophisticated filtering and measuring was used for science's sake.

The pomegranate has "been revered through the ages for its medicinal uses," write the researchers.

Antioxidants in pomegranates fight inflammation and may also counter cancer and heart disease.

In May, researchers reported that pomegranate juice may help prevent the return of prostate cancer. In March, another study showed that pomegranate juice may fight hardening of the arteries.
Pomegranate Season

Pomegranates are in season in the U.S. in the fall. They've got a thick, red, leathery skin. The seeds inside are the edible part.

Want to try a pomegranate? You might want to wear a bib or old clothes. The seeds leave a very strong stain and are used as a dye.

Arthritis.Recipes

These recipes are packed with great taste, and the good nutrition that helps
limit the joint swelling of arthritis, keeps bones strong, and promotes overall
health! Some dishes are super easy, and others take a little bit more
preparation. But all provide delicious, balanced meals.



Breakfast



Pumpkin Pie Smoothie

Enjoy with a whole grain English muffin

1/2 cup canned pumpkin

1/2 cup milk

Pinch cinnamon

2 teaspoons sugar or artificial sweetener to taste



Combine all ingredients in a blender or food processor. Whip on high speed for 2
to 3 minutes, or until frothy. Serve immediately. Makes about 1 1/2 cups.



Peanut Butter Banana Smoothie

Pair this one up with a whole-grain English muffin, too

3/4 cup plain yogurt

1 medium banana

2 tablespoons peanut butter

2 ice cubes



Combine all ingredients in a blender or food processor. Whip on high speed for 2
to 3 minutes or until frothy. Serve immediately. Makes about 1 1/2 cups.



Berry Fluffy Pancakes

Serve with a glass of orange juice fortified with calcium and vitamin D

1 cup plain nonfat or low-fat yogurt

1 large egg

1 cup pancake mix

1 cup fresh blueberries or raspberries



In a bowl, combine yogurt and egg. Mix well. Add pancake mix and blend just to
combine. Lightly oil or spray a nonstick pan or griddle. Ladle out 2 tablespoons
batter for each pancake. Drop a few berries onto pancake. When edges are firm,
turn pancakes and cook 1 minute more. Serve immediately. This will give you 3
pancakes, but you can make extra and freeze.



Jazz-y Oatmeal

Prepare a packet or two of regular instant oatmeal in the microwave according to
directions, with milk or soy beverage. After cooking, stir in 1/2 cup applesauce
and 1/4 cup raisins (more if using 2 packets) and pinch of cinnamon, if desired.



Confetti Cottage Cheese

Add 1/4 cup dried pre-chopped apricots; 2 tablespoons chopped walnuts; and 1
tablespoon ground flaxseed to 1 cup low-fat cottage cheese. Serve on top of a
toasted Heart Healthy Cinnamon Raisin bagel from Sara Lee. One bagel supplies 48
grams of whole grain, the minimum amount experts recommend you get each day.



Waffle Sandwich

Toast two high-fiber waffles, such as Kashi Go Lean Original Whole Grain. Spread
each waffle with 1 tablespoon peanut butter or almond butter to make a sandwich.
Have with a glass of low-fat milk and fruit.



Lunch



Easy English Muffin or Pita Pizzas

Top each half of a whole-grain English muffin or a small whole-wheat pita round
with 1/4 cup marinara sauce and 1/4 cup grated cheese. Broil in a toaster oven
or in the regular oven for about 5 minutes, or until the cheese melts. Cool
before eating. Serve with a glass of orange juice fortified with calcium and
vitamin D.



Soup du Jour

Add an equal amount of cooked small whole grain pasta, such as DaVinci's whole
wheat elbows or leftover brown rice to a can of lentil or split pea soup (reserve
half for another meal). Serve with fruit and a glass of milk or 8 ounces low-fat
yogurt.



Scrambled Egg and Salsa Sandwich

Scramble one or two eggs. Fill each half of a small whole-wheat pita pocket with
the cooked egg. Top with mild salsa or ketchup and 1/4 cup grated cheddar cheese.
Enjoy with fruit or baby carrots and a glass of low-fat milk.



A Better Burger

Microwave a Perdue Frozen Seasoned Chicken Burger to have on a whole grain bun.
Or go vegetarian with Boca Burger's All American Meatless Burger. Pair with baby
carrots or presliced celery sticks and a glass of low-fat milk.



Dinner



No-Cook Roast Chicken Dinner

Purchase one or two (depending on how many are eating) roasted chickens from the
supermarket. Pick up pre-cut salad greens and a package of grape tomatoes. Add
chopped fresh, frozen, or low-sodium canned vegetables to your cart. Serve with
whole grain bread from the bakery. (Use leftover chicken the next day with
whole-wheat bread or sandwich wraps for lunch!)



Go With Grains

Add leftover chopped chicken, turkey, or beef, and cooked vegetables to tabouleh
mix from Fantastic Foods or Near East. Near East also makes Whole Grain Blends
that go well with meat and vegetables. Serve the combo over salad greens.



Simple Skillet Salmon for Two

Combine 1/2 cup orange juice, 2 tablespoons reduced-sodium teriyaki sauce, 1
tablespoon honey, and 1/2 teaspoon ground ginger in a small bowl. Transfer to
skillet and bring to low boil. Add 1 pound of salmon fillet, skin side up. Cover
and cook over low to medium heat until fish is flaky in the center. Serve over
cooked chopped frozen spinach and enjoy with couscous.



Diner Dinner

Prepare a 2-egg omelet with leftover or frozen chopped green vegetables and 1/4
cup feta or cheddar cheese. Enjoy with whole grain toast and fruit.



Spaghetti Supper

Start with store-bought meatballs and a jar of tomato sauce. Or, in place of
meatballs, add canned, drained chickpeas or browned 100% ground turkey breast to
spaghetti sauce for protein. Toss with frozen chopped veggies for fiber,
vitamins, and minerals.



Pizza Party

Order a thin crust vegetable pizza. Have with it canned or frozen fruit, and a
salad prepared from pre-washed greens, with grape tomatoes and grated carrots.

Arthritis and Simple Meals

Everyone wants to save time and energy in the kitchen. It's particularly important when aching joints from arthritis turn preparing a meal into a monumental task. We've put together some ideas for easy meals that take the strain off your hands and body and don't wear you out. At the same time, they manage to deliver great taste, as well as the nutrition you need to limit swelling from arthritis and stay strong.

And here's a tip: when you are feeling up to cooking, make extra. That way, you'll always have healthy food around to eat on your lower-energy days. If meal prep is largely out of the question for you, consider using your local Meals on Wheels program.
Frozen Meals for Bad Arthritis Days

Frozen entrees are quick and easy, especially when your arthritis is keeping you out of the kitchen. But they are notoriously high in sodium and low in fiber. If you know what to look for, there are plenty of good choices in the freezer aisle to serve as the centerpiece of a nutritious meal. Look for dishes that supply 800 milligrams of sodium or less; a minimum of 15 grams of protein; and at least four grams of fiber.

Even the healthiest frozen entrees skimp on produce and whole grains. Supplement with a cup of fresh or frozen cooked vegetables, and a slice of whole grain bread to make a complete meal.
Nearly-a-Meal Convenience Foods

Supermarkets abound with convenience foods that could be considered near-meals, easy for anyone with arthritis. Like most processed foods, they supply more sodium than you need, so look for lower-sodium varieties. These meal starters come up short on protein so they need to be supplemented with fruits, vegetables, whole grains, and dairy to make a balanced meal.

When arthritis makes cooking tough, enjoy a protein-packed bean soup such as lentil, black bean, or split pea. Invest in a reliable electric can opener to make it easier on yourself. You can also pick up a pre-roasted chicken, a breakfast burrito, sushi or other ready-made foods at most grocery stores these days. Plus, marinated albacore (white) tuna steaks and salmon fillets are available in easy-to-open packages and are ready to eat in seconds for lunch or dinner. In a pinch, even a can of season tuna - served on six crackers - makes an instant healthy meal.
The Role of Liquid Meals in Your Arthritis Diet

Liquid meals supply many essential vitamins and minerals, but they lack adequate protein and fiber to be considered a real meal. Plus, they aren't particularly satisfying and can leave you wanting more. And they are relatively expensive. But in spite of all that, they are not without merit; convenience is one of their virtues. Pair them with a piece or two of whole-grain toast or a whole-grain waffle and fruit to round out their nutritional power for an arthritis friendly meal.

Check the label to make sure the liquid meal contains a variety of vitamins and minerals. Most 8-ounce nutritional supplement drinks are fortified to provide 25% of the vitamins you need each day.

Treat Paget’s disease.Calcitonin

A drug currently used to treat osteoporosis may also help protect the bone and slow or perhaps even halt the progression of osteoarthritis, according to early research.

A new study shows treatment with calcitonin, a hormone, effectively prevented erosion of knee cartilage in rat models of osteoarthritis. Osteoarthritis is also known as degenerative joint disease and is related to cartilage breakdown in the joints which can lead to joint damage.

Calcitonin is currently used to treat Paget’s disease of the bone and osteoporosis, as previous studies have shown that the hormone reduces bone loss. But researchers say these results suggest that calcitonin may also help prevent the joint destruction associated with osteoarthritis (OA).
New Option for OA

Osteoarthritis is the most common joint disorder and affects more than 10% of Americans. Treatment usually addresses easing the pain caused by joint stiffness and inflammation associated with osteoarthritis.

To date, no drug has been approved to prevent the gradual loss of cartilage caused by the disease. But a new understanding of the progression of the disease in recent years has prompted a surge of interest in developing disease-modifying osteoarthritis drugs aimed at potentially preventing the disease in those at risk, such as postmenopausal women.

In the study, published in Arthritis & Rheumatism, researchers compared the effects of treating female rats that had their ovaries removed with estrogen alone and estrogen plus calcitonin.

Loss of estrogen from age or other causes increases the risk of osteoporosis. Other research has suggested that hormone replacement therapy helps protect postmenopausal women from osteoarthritis. This study showed that estrogen therapy and calcitonin given to rats helped reduce the rise in compounds indicative of joint destruction of osteoarthritis.

Calcitonin and estrogen also worked effectively in protecting against surface erosions of joint cartilage.

“Calcitonin treatment may counter the acceleration of cartilage degradation and the related rise of surface erosions,” writes researcher Bodil-Cecilie Sondergaard, of Nordic Bioscience Diagnostics in Herlev, Denmark, and colleagues.

Researchers say these results are only preliminary, but they suggest that calcitonin merits further research in human clinical trials.

The FDA has approved Voltaren Gel

The FDA has approved Voltaren Gel, the first prescription skin gel to treat osteoarthritis joint pain.

Voltaren Gel contains diclofenac sodium, a nonsteroidal anti-inflammatory drug (NSAID) that's also in oral Voltaren. The gel can be applied to joints that hurt because of osteoarthritis.

Osteoarthritis is the most common form of arthritis. It happens when the cartilage in joints breaks down and wears away.

The FDA approved Voltaren Gel based on studies that together included more than 900 patients with knee or hand osteoarthritis, according to Novartis, which makes Voltaren Gel.

Voltaren Gel was shown to cut pain in knee and hand osteoarthritis, states Novartis.

It wasn't evaluated for use on joints of the spine, hip, or shoulder, according to the drug's label.

The most common side effects reported in clinical trials of Voltaren Gel were skin reactions; 7% of patients had reactions on the place where the gel was applied..

Shock-absorbing athletic shoes and clogs may be bad for arthritic knees

Those shock-absorbing athletic shoes and clogs designed to protect and cushion the feet may be bad for arthritic knees.

When researchers examined the effects of different types of footwear on people with knee osteoarthritis, they found that going barefoot put less stress on knee joints than wearing foot-stabilizing walking shoes or clogs.

Flip-flops and a flexible walking shoe were also better choices for minimizing impact to the knees during normal walking.

The researchers determined this by assessing a standard measure of knee joint impact, known as knee load.

"Knee loads play an important role in the progression of knee osteoarthritis," researcher Najia Shakoor, MD, of Rush Medical College, says in a news release. "Shoes have traditionally been engineered to provide foot comfort and little previous attention has been directed to the effects that shoes may have on loading of osteoarthritic knees."

She notes that flat, flexible shoes were best for minimizing the impact on knee joints.

The findings were presented at the annual meeting of the American College of Rheumatology in Boston.
Impact of Shoes on Osteoarthritis

According to the Arthritis Foundation, 21 million Americans have osteoarthritis, a chronic disease in which the cartilage that serves as a shock absorber in the joints is broken down over time.

Also known as degenerative joint disease, osteoarthritis is a leading cause of disability among adults. Obesity, age, and joint overuse or injury are risk factors for the condition.

In a 2006 study with a similar design, Shakoor and colleagues reported that going barefoot put less stress on knee joints than wearing everyday walking shoes.

In their latest study, the researchers examined knee loads among 13 women and three men (average age 56 years) with knee osteoarthritis while they were barefoot, and then while they wore a popular brand of clogs, a foot-stabilizing walking shoe, a flat, flexible walking shoe, and flip-flops.

Compared to walking barefoot, the clogs and foot-stabilizing walking shoes were associated with significantly higher knee loading.

"These results highlight the importance of re-evaluating the design of modern day shoes in terms of their effects on knee loads and knee osteoarthritis," the researchers write.
More Study Needed

Rheumatologist Dennis Boulware, MD, says he was surprised by the finding that shoes that are good for ailing feet may not be good for ailing knees.

"This does make me a bit concerned about advising patients about certain types of footwear," he says. "I will certainly pay more attention to knee complaints when I put someone in [foot-stabilizing] shoes for foot problems."

Boulware, who is chief of rheumatology for Kaiser Permanente, Honolulu, adds that larger studies are needed to confirm the findings.

"I am somewhat skeptical because of the small size of the study," he says. "But this is clearly something we need to know more about."

Show a risk for knee osteoarthritis

Is your ring finger longer than your index finger? That may show a risk for knee osteoarthritis, especially in women, a British study shows.

Osteoarthritis is the most common type of arthritis. In osteoarthritis, the protective cartilage that cushions the ends of bones within joints gradually wears away. It can affect almost any joint in the body but commonly involves the weight-bearing joints: the knees, hips, and spine.

Osteoarthritis becomes more common with age and extra weight. Finger length may also be a risk factor, according to the new British study.

It's not about whether your fingers are long or short. Instead, it's about the ratio between the length of your index finger (the second finger, counting from the thumb) and your ring finger (the fourth finger).

Handful of Osteoarthritis Risk

The British study included more than 2,000 people with severe knee and/or hip osteoarthritis and more than 1,100 people without knee or hip osteoarthritis.

The researchers, based at England's University of Nottingham, eyeballed the length of participants' ring and index fingers, following up with hand X-rays for precise measurements.

The key finding: People whose index finger was shorter than their ring finger were about twice as likely to have knee osteoarthritis, compared with other participants.

That pattern was stronger for women than for men. Among women, those with an index finger shorter than their ring finger were three times more likely to have knee osteoarthritis.

The finding may also be true for hip osteoarthritis, but because most participants with hip arthritis also had knee osteoarthritis, it was hard for the researchers to confirm that.

Other osteoarthritis risk factors -- including age, sex, BMI (body mass index, which relates height to weight), previous joint injuries, and physical activity -- didn't explain the results.

Rheumatology professor Michael Doherty, MD, and colleagues aren't sure how to explain their findings. They note that men are more likely than women to have index fingers that are shorter than ring fingers, so hormonal factors may be involved, but that's not certain.

Arthritis .Alternative Medicine

Arthritis .Alternative Medicine

Homeopathy may improve pain, joint tenderness, stiffness, and grip strength, especially when used in conjunction with NSAIDs.

Fish oil has been shown to reduce arthritis inflammation, lessen the need for painkillers, and possibly decrease joint stiffness. A diet low in animal and dairy fats may have similar effects. Excellent sources of fish oil include EPA/DHA capsules and oily fish such as salmon and mackerel.

At least a dozen different herbs have been used to ease the symptoms of both osteoarthritis and rheumatoid arthritis; most are considered anti-inflammatories. Ask your doctor about using any herbs, since they can interact with each other or with medication you are taking. In most cases, lack of careful studies means little is known about long-term effects. Herbs that have been used for arthritis are powdered ginger, borage seed oil, or devil's claw to reduce pain and swelling. Stinging nettles or turmeric may also lessen arthritis pain, stiffness, and inflammation.

Ayurvedic medicine uses herbal compounds internally and externally for arthritis symptom relief. Topical curcumin may help relieve the inflammation of rheumatoid arthritis; if taken in capsule form, it can reduce morning stiffness and boost endurance. In one study, a combination of Withania somnifera, Boswellia serrata, and Cucurma longa caused a significant drop in pain and disability for people with osteoarthritis.
At-Home Remedies for Arthritis

Heat and rest - traditional remedies for arthritis pain - are very effective in the short run for most people with the disease. Overweight sufferers should lose weight, especially when arthritis affects the lower back, knees, and legs. Consult a registered dietician who can help you plan a healthy weight-loss program.

In addition to treatments recommended by your doctor, you can use dry heat from a heating pad or moist heat in the form of a hot bath or a hot-water bottle wrapped in a towel to help relieve arthritis pain and stiffness. Regular exercise is important to keep the joints mobile. People with weakened, badly deformed fingers from rheumatoid arthritis benefit from specially designed utensils and door and drawer handles; people suffering weakness in the legs and arms can use special bathroom fixtures, especially tub rails and elevated toilet seats.

Though arthritis is not preventable, many people are able to prevent disability with a well-designed treatment program, including medications, exercise, and physical therapy when needed.

Surgery .Arthritis

Surgery for Arthritis

Various forms of surgery may be needed to reduce the discomfort of arthritis or to restore mobility or joint function. Synovectomy is the removal of damaged connective tissue lining a joint cavity, and allows the body to regenerate new, healthy tissue in its place. This operation is most common in the knee. In cases of severe arthritic damage to the neck or foot, bones can be surgically removed or fused. Although movement is limited after such surgery, the operations relieve excruciating pain and help prevent further damage to nerves or blood vessels.

If arthritis pain and inflammation become truly unbearable, or arthritic joints simply refuse to function, the answer may lie in surgical joint replacement. Today, hip and shoulder joints - as well as smaller joints in elbows, knees, and fingers - can be replaced with reliable artificial joints made of stainless steel and plastic. This type of surgery can dramatically improve function and mobility.
Arthritis Pain Management

Because one of the most trying aspects of this disease is learning to live with arthritis pain, many doctors recommend training in pain management, including cognitive therapy. The National Institutes of Health has found that cognitive behavioral therapy, using education and behavior modification alongside relaxation techniques, is better than routine care for relieving arthritis pain. Such programs focus on improving patients' emotional and psychological well-being by teaching them how to relax and conduct their daily activities at a realistic pace. Learning to overcome mental stress and anxiety can be the key to coping with the physical limitations that may accompany chronic rheumatoid arthritis and osteoarthritis. Cognitive therapy may include various techniques for activity scheduling, imaging, relaxation, distraction, and creative problem-solving.
Alternative Medicine for Arthritis

A variety of alternative therapies are used for arthritis. Let your doctor know if you're considering them.

Some studies suggest that glucosamine and chondroitin supplements are as effective as NSAIDs for reducing pain, swelling, and stiffness in osteoarthritis. Studies in 2001 show some promise that they may slow the progression of osteoarthritis as well. More studies are underway to further investigate this. Typical doses are 1500 mg for glucosamine and 1200 mg for chondroitin daily. Glucosamine can raise blood sugar, so be sure to talk to your doctor before taking it, especially if you have diabetes. The antibiotic doxycycline may also show some potential in delaying the progression of osteoarthritis by inhibiting enzymes that break down cartilage. More research is needed to confirm these results.

The National Institutes of Health considers acupuncture an acceptable alternative treatment for osteoarthritis. Studies have shown that acupuncture helps reduce pain, may significantly lessen the need for painkillers, and can help increase range of motion in affected joints.

Available over-the-counter since 1999, the supplement SAMe has been shown in some studies to be as effective against osteoarthritis pain as NSAIDs, with the added benefit of fewer side effects.

Treatments for Arthritis

Treatments for Arthritis

Arthritis treatment generally includes occupational or physical therapy, exercise, drugs, and sometimes surgery to correct joint damage. Treatments for osteoarthritis can help relieve pain and stiffness, but the disease may continue to progress. The same was true for rheumatoid arthritis in the past. But treatments in recent years have been able to slow or stop progression of joint damage.

The duration and intensity of pain and discomfort depend on the type of arthritis and the degree of severity.


Conventional Medicine

In the case of localized pain, stiffness, and immobility, the typical three-stage arthritis treatment consists of medication to relieve pain and inflammation, rest to let injured tissues heal themselves, and exercise to rebuild mobility and strength.
Joint Protection

Learning to protect your joints is an important part of arthritis treatment. With the help of an occupational therapist, you can learn easier ways to do your normal activities, such as avoiding positions that strain your joints, using your strongest joints and muscles while sparing weaker ones, wearing braces or supports for certain joints and using grab bars in the bath, modified door knobs, canes or walkers, as well as using devices to help you with tasks such as opening jars or pulling up socks and zippers.

Your doctor may recommend pain relievers combined with regimens of heat, rest and exercise, physical therapy, and controlled application of deep heat to soothe affected joints.


Arthritis Medication

To reduce pain and inflammation in mild cases of rheumatoid arthritis and osteoarthritis, your doctor will probably prescribe aspirin or another nonsteroidal anti-inflammatory drug (NSAID), such as ibuprofen. Your doctor may also suggest acetaminophen for osteoarthritis.

In more advanced cases, your doctor may recommend corticosteroid joint injections - strong anti-inflammatories - to ease the pain and stiffness of arthritic joints. Depending on the individual, results range from temporary relief to long-lasting suppression of symptoms. Doctors are also using hyaluronate gel-like solutions in joint injections to further restore the cushion and lubricating properities of normal joint fluid thereby minimizing pain. Some examples are Hyalgan, Synvisc, Supartz, and Orthovisc.

In the early 1900s, researchers discovered that certain compounds containing gold, given orally or by injection, gave relief to some people who have rheumatoid arthritis and caused total remission in others.
Note, however, that because the side effects of gold treatment can range from minor skin rash to severe blood and kidney disorders, this treatment is generally approached with caution.

Newer treatments using low doses of chemotherapy medications (methotrexate) have produced dramatic improvements in severe rheumatoid arthritis, and these treatments show great promise of preserving joint function. Other strong medications that have come along since methotrexate are Arava, Azulfidine, Enbrel, Imuran, Neoral, Plaquenil, Remicade, Humira, Kineret, Rituxan, and Orencia. In general, they work by suppressing the overactive immune system. Apheresis is another treatment for rheumatoid arthritis that removes antibodies from the blood.

Specific arthritis treatment will depend on the nature and seriousness of the underlying condition. The major concern is for healing the affected area before more serious problems occur. Treatment of infectious arthritis typically involves large intravenous doses of antibiotics as well as drainage of excess fluid from the joints.

Symptoms of osteoarthritis

Symptoms of osteoarthritis

Osteoarthritis is a disease of the joints. Unlike many other forms of arthritis that are systemic illnesses, such as rheumatoid arthritis and systemic lupus, osteoarthritis does not affect other organs of the body. The most common symptom of osteoarthritis is pain in the affected joint(s) after repetitive use. Joint pain is usually worse later in the day. There can be swelling, warmth, and creaking of the affected joints. Pain and stiffness of the joints can also occur after long periods of inactivity, for example, sitting in a theater. In severe osteoarthritis, complete loss of cartilage cushion causes friction between bones, causing pain at rest or pain with limited motion.

Symptoms of osteoarthritis vary greatly from patient to patient. Some patients can be debilitated by their symptoms. On the other hand, others may have remarkably few symptoms in spite of dramatic degeneration of the joints apparent on x-rays. Symptoms also can be intermittent. It is not unusual for patients with osteoarthritis of the hands and knees to have years of pain-free intervals between symptoms.

Osteoarthritis of the knees is often associated with obesity or a history of repeated injury and/or joint surgery. Progressive cartilage degeneration of the knee joints can lead to deformity and outward curvature of the knees referred to as "bow legged." Patients with osteoarthritis of the weight bearing joints (like the knees) can develop a limp. The limping can worsen as more cartilage degenerates. In some patients, the pain, limping, and joint dysfunction may not respond to medications or other conservative measures. Therefore, severe osteoarthritis of the knees is one of the most common reasons for total knee replacement surgical procedures in the United States.

Osteoarthritis of the spine causes pain in the neck or low back. Bony spurs that form along the arthritic spine can irritate spinal nerves, causing severe pain, numbness, and tingling of the affected parts of the body.

Osteoarthritis causes the formation of hard bony enlargements of the small joints of the fingers. Classic bony enlargement of the small joint at the end of the fingers is called a Heberden's node, named after a very famous British doctor. The bony deformity is a result of the bone spurs from the osteoarthritis in that joint. Another common bony knob (node) occurs at the middle joint of the fingers in many patients with osteoarthritis and is called a Bouchard's node. Dr. Bouchard was a famous French doctor who also studied arthritis patients in the late 1800s. The Heberden's and Bouchard's nodes may not be painful, but they are often associated with limitation of motion of the joint. The characteristic appearances of these finger nodes can be helpful in diagnosing osteoarthritis. Osteoarthritis of the joint at the base of the big toes leads to the formation of a bunion. Osteoarthritis of the fingers and the toes may have a genetic basis, and can be found in numerous women members of some families.

Best exercises for knee arthritis







Low-Impact Activities

Being active may also help you lose weight, which takes pressure off joints. Other exercises that are easy on the knees: biking, swimming, and water aerobics. Water exercise takes weight off painful joints. Many community and hospital wellness centers, YMCAs, and pools offer classes for people with arthritis.

Don't give up favorite activities, like golf. Talk to your doctor or physical therapist about modifying painful moves.














Walking

With stiff or sore knees, walking may not seem like a great idea. But it's one of the best exercises for knee arthritis. It can reduce joint pain, strengthen leg muscles, and improve flexibility -- and it's good for your heart. The best part -- no gym membership needed.

Good form is key: Look forward, walk tall. Keep arms and legs moving, relaxed. Always ask your doctor before starting exercise when you have osteoarthritis.
















Step Ups

This move helps strengthen your legs for climbing stairs. Face a stable step, both feet on the ground. Step up with your left foot. Follow with your right foot. Stand on top, tall and with both feet flat. Climb down in reverse: right foot down first, then left. Do 10 times. Rest, then repeat another 10 times. Then repeat, starting with right leg first. Too hard? Use a railing, wall, or lamppost for balance. Or try a lower step.














One Leg Balance

Your goal is to do this hands-free. Steady yourself on a chair, if needed. First, shift your body weight to one leg but do not lock your knee straight. Slowly raise the other foot off the ground, balancing on your standing leg. Hold for 20 seconds. Lower raised foot to the ground. Do twice, then switch legs. This move helps when getting out of cars or bending.

Too easy? Balance for a longer time. Or try with your eyes closed.














Sit to Stand

Practice this move to make standing easier. Place two pillows on chair. Sit on top, with your back straight, feet flat on floor (see left). Use your leg muscles to slowly and smoothly stand up tall. Then, slowly lower yourself back down to sitting. Be sure your bent knees don’t move forward of your toes. Try with arms crossed (see left) or loose to your side.

Too hard? Add pillows or use a chair with armrests and help push up with your arms.
















Side Leg Raise

Hold back of chair for balance. Place your weight on left leg. Lift right leg out to the side. Keep right leg straight and outer leg muscles tensed. Don't slouch. Lower right leg and relax. Repeat 10 times. Rest. Do another 10, then repeat with left leg.

Too hard? Increase leg height over time. After a few workouts, you’ll be able to raise your leg higher.













Heel Raise

Hold back of chair for support. Stand straight and tall. Lift heels off ground and rise up on toes of both feet. Hold for five seconds. Slowly lower both heels to ground. Repeat 10 times. Rest. Do another 10.

Too hard? Do the same exercise, only sitting in a chair.














Pillow Squeeze

This move helps strengthen the inside of your legs to help support your knee. Lie on your back, both knees bent. Place a pillow between knees.

Squeeze knees together, squishing pillow between them. Hold for five seconds. Relax. Repeat 10 times. Rest, then do another set of 10.

Too hard? You can also do this exercise while seated. See photo to right.














Seated Hip March

This move can strengthen hips and thigh muscles to help with daily activities, such as walking or rising from a chair.

Sit up straight in chair. Slightly kick back your left foot but keep toes on the floor. Lift your right foot off the floor, keeping knee bent. Hold right leg in the air five seconds. Slowly lower your foot to the ground. Repeat 10 times. Rest and do another 10, then switch legs. Too hard? Use your hands to help raise your leg.














Quad Set

Is the straight leg raise too tough? Do quad sets instead. With these you don’t raise your leg. Simply tighten the thigh muscles, also called the quadriceps, of one leg at a time.

Start by lying on the floor. Keep both legs on ground, relaxed. Flex and hold left leg tense for five seconds, as seen in right-hand photo. Relax. Do two sets of 10. Then, switch to other leg.
















Straight Leg Raise

To try this leg strengthening move, lie on the floor. Prop your back up on your elbows. Bend your left knee, keeping foot on floor. Keep the right leg straight, toes pointed up. Tighten thigh muscles of your right leg. Slowly and smoothly use your thigh muscles -- not your back -- to raise your leg.

Pause, as seen above, for five seconds. With thigh still tight, slowly lower leg to ground. Relax. Repeat 10 times. Rest. Do another 10; then switch legs.












Calf Stretch

Stretching exercises loosen muscles, improve flexibility, and help prevent pain and injury.

Use a chair for balance. Bend your right leg. Step back with left leg, slowly straightening it behind you. Press left heel towards the floor. Feel the stretch in your back leg.

For more of a stretch: Lean forward, bending the right knee deeper. Don't let the right knee go past your toes. Hold for 20 seconds. Do twice, then switch legs.







Hamstring Stretch

Warm up with a five-minute walk. Then, stretch. Lie down. Loop a bed sheet around your right foot. Use sheet to help pull and stretch leg up. Hold for 20 seconds. Repeat twice, then switch legs. Stretching is one of three important types of exercises for knee OA. Range of motion or stretching exercises keep you limber. Strengthening exercises build muscle strength to stabilize weak joints. Aerobic exercises, like walking, help lung and heart fitness.








How Much Exercise?

Start with a little. If you can do it without pain, do more next time. Aim for 30 minutes a day.
Over time you’ll build your leg muscles to support your knee and increase flexibility.

Some muscle soreness is normal, but hurting or swollen joints need rest. Take a break and ask your doctor’s advice. Ice painful joints and take acetaminophen or an anti-inflammatory pain reliever, like ibuprofen or naproxen, if your doctor says it's OK.